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Global Brain Connectivity Explains 10 Percent of Variance in Individual Intelligence

August 2, 2012 / Klint Finley

Science Daily reports on a recent study using magnetic imaging found that about 6.7% of variation in individual intelligence can be predicted by the overall size of the brain, another 5% can be predicted by the size of the lateral prefrontal cortex and another 10% can be predicted by the strength of the connection between the left lateral prefrontal cortex and the rest of the brain. From the story:

“This study suggests that part of what it means to be intelligent is having a lateral prefrontal cortex that does its job well; and part of what that means is that it can effectively communicate with the rest of the brain,” says study co-author Todd Braver, PhD, professor of psychology in Arts & Sciences and of neuroscience and radiology in the School of Medicine. Braver is a co-director of the Cognitive Control and Psychopathology Lab at Washington University, in which the research was conducted.

One possible explanation of the findings, the research team suggests, is that the lateral prefrontal region is a “flexible hub” that uses its extensive brain-wide connectivity to monitor and influence other brain regions in a goal-directed manner.

Science Daily: Brain Imaging Can Predict How Intelligent You Are: ‘Global Brain Connectivity’ Explains 10 Percent of Variance in Individual Intelligence

(via Ryan Yonck)

Jonah Lehrer Resigns From The New Yorker Over Fabricated Quotes

July 30, 2012 / Klint Finley

Science journalist Jonah Lehrer, whose articles I have linked to from Technoccult in the past, stepped down from the New Yorker today after admitting to fabricated Bob Dylan quotes in his book Imagine. Here’s Lehrer’s statement, as quoted by Julie Bosman for The New York Times:

“Three weeks ago, I received an email from journalist Michael Moynihan asking about Bob Dylan quotes in my book ‘Imagine,’ ” Mr. Lehrer said in a statement. “The quotes in question either did not exist, were unintentional misquotations, or represented improper combinations of previously existing quotes. But I told Mr. Moynihan that they were from archival interview footage provided to me by Dylan’s representatives. This was a lie spoken in a moment of panic. When Mr. Moynihan followed up, I continued to lie, and say things I should not have said.”

“The lies are over now. I understand the gravity of my position. I want to apologize to everyone I have let down, especially my editors and readers. I also owe a sincere apology to Mr. Moynihan. I will do my best to correct the record and ensure that my misquotations and mistakes are fixed. I have resigned my position as staff writer at The New Yorker.”

Full Story: The New York Times: Jonah Lehrer Resigns From The New Yorker After Making Up Dylan Quotes for His Book

(via Coe Douglas)

Finding the Right Type of Meditation for You Might be Key to Meditation Success

July 15, 2012 / Klint Finley

Did you give meditation a chance and decide it’s not your cup of tea? New research suggests you could be missing out on all the health benefits of meditation by simply starting out with a technique not well matched to your personal tastes. […]

Burke and colleagues recently conducted a study of college students new to meditation and their preferences among four meditation techniques — mantra, mindfulness, zen, and qigong visualization. […]

Published on July 7 in the journal Explore: The Journal of Science and Healing, the findings reveal that by finding a form of meditation that works for you, you are less likely to quit. The result of sticking with it? Research-backed benefits of reduced stress, lower blood pressure, and help with addiction problems.

Full Story: NY Daily News: The right kind of meditation for you; Mantra, mindfulness, zen, and qigong visualization are different ways to relax

The paper is here, behind a paywall.

The Weaponization of Neuroscience

July 12, 2012 / Klint Finley

Jon Bardin wrote for The Chronicle of Higher Education on how science can be weaponized, even decades after it’s conducted. For example, this DARPA project is based on unrelated research from the 1960s:

In a small, anonymous office in the Trump Tower, 28 floors above Wall Street, a man sits in front of a computer screen sifting through satellite images of a foreign desert. The images depict a vast, sandy emptiness, marked every so often by dunes and hills. He is searching for man-made structures: houses, compounds, airfields, any sign of civilization that might be visible from the sky. The images flash at a rate of 20 per second, so fast that before he can truly perceive the details of each landscape, it is gone. He pushes no buttons, takes no notes. His performance is near perfect.

Or rather, his brain’s performance is near perfect. The man has a machine strapped to his head, an array of electrodes called an electroencephalogram, or EEG, which is recording his brain activity as each image skips by. It then sends the brain-activity data wirelessly to a large computer. The computer has learned what the man’s brain activity looks like when he sees one of the visual targets, and, based on that information, it quickly reshuffles the images. When the man sorts back through the hundreds of images—most without structures, but some with—almost all the ones with buildings in them pop to the front of the pack. His brain and the computer have done good work.

Chronicles of Higher Education: From Bench to Bunker

(Thanks Justin!)

Synesthesia May Explain Aura Reading

June 18, 2012 / Klint Finley

From Science Daily:

In basic neurological terms, synesthesia is thought to be due to cross-wiring in the brain of some people (synesthetes); in other words, synesthetes present more synaptic connections than “normal” people. “These extra connections cause them to automatically establish associations between brain areas that are not normally interconnected,” professor Gómez Milán explains. New research suggests that many healers claiming to see the aura of people might have this condition. […]

Many local people attribute “paranormal powers” to El Santón, because of his supposed ability to see the aura of people “but, in fact, it is a clear case of synesthesia,” the researchers explained. According to the researchers, El Santón has face-color synesthesia (the brain region responsible for face recognition is associated with the color-processing region); touch-mirror synesthesia (when the synesthete observes a person who is being touched or is experiencing pain, s/he experiences the same); high empathy (the ability to feel what other person is feeling), and schizotypy (certain personality traits in healthy people involving slight paranoia and delusions). “These capacities make synesthetes have the ability to make people feel understood, and provide them with special emotion and pain reading skills,” the researchers explain.

Full Story: Science Daily: Synesthesia May Explain Healers Claims of Seeing People’s ‘Aura’

(via Matt Staggs)

I’ve long suspected this to be true. I’ve met a couple of people who claimed to be able to see auras and didn’t seem to be liars or crazy.

Fructose Fogs the Brain New Study on Rats Suggests

May 16, 2012 / Klint Finley

A high intake of fructose impairs the cognitive abilities of rats by interfering with insulin signaling, but omega-3 fatty acids (n-3) reduces those negative effects effects according to a study from the Department of Integrative Biology and Physiology UCLA published in Journal of Physiology.

Although headlines today, including my own, emphasize the study’s findings regarding the impairing effects of high levels of fructose, the study also highlights the importance of n-3 acids, specifically DHA, to cognitive function. The authors of the study conclude: “In terms of public health, these results support the encouraging possibility that healthy diets can attenuate the action of unhealthy diets such that the right combination of foods is crucial for a healthy brain.”

The study, conducted by Rahul Agrawal1 and Fernando Gomez-Pinilla, consisted of four groups of six rats:

one group ate an n-3 deficient diet with a fructose solution
one group ate an n-3 deficient diet without a fructose solution
one group ate an n-3 sufficient diet with a fructose solution
one group ate an n-3 sufficient diet without a fructose solution

Each group was tested on a Barnes maze, a standard measure of spatial learning and memory in rodents. Prior to beginning their special diets all of the rats had been trained in the maze for a five days were found to be of equal cognitive condition.

The study found that an n-3 deficient diet hampered the rats’ performance on the maze, and that adding high fructose intake to an n-3 deficient diet made things substantially worse. The rats with an n-3 sufficient diet but a high level of fructose did significantly better than those with a n-3 deficient diet and a high level of fructose, but still did worse than those with a deficient n-3 level but no fructose. Here’s an illustration of the latency in completing the maze (lower is better):

Comparison of latency times in Barnes maze test

The study notes: “Although there was a preference towards fructose drinking in comparison to the food intake, no differences were observed in body weight and total caloric intake, thus suggesting that obesity is not a major contributor to altered memory functions in this model.”

Full Paper: The Journal of Physiology: ‘Metabolic syndrome’ in the brain: deficiency in omega-3 fatty acid exacerbates dysfunctions in insulin receptor signalling and cognition

This is a new study and has yet to be replicated, and so far its implications for human diets is unclear. “We’re not talking about naturally occurring fructose in fruits, which also contain important antioxidants,” Gomez-Pinilla said in a pres release. “We’re concerned about high-fructose corn syrup that is added to manufactured food products as a sweetener and preservative.”

Although studies have found positive benefits in taking DHA supplements (see Wikipedia for an overview), previous study by Nutritional Sciences Division at King’s College London on the DHA levels in vegans and vegetarians concluded that although those who don’t eat meat have significantly lower levels of DHA “There is no evidence of adverse effects on health or cognitive function with lower DHA intake in vegetarians.” However, there are now a number of algae based vegan DHA supplements.

Conjoined Twins with Connected Brains

May 3, 2012 / Klint Finley

Krista and Tatiana Hogan are conjoined twins joined at the head. But unlike all other known craniopagus twins the Hogans’ brains are also linked, by a small bridge connected the thalamus of one girl to the thalamus of the other. Susan Dominus wrote for The New York Times last year:

Suddenly the girls sat up again, with renewed energy, and Krista reached for a cup with a straw in the corner of the crib. “I am drinking really, really, really, really fast,” she announced and started to power-slurp her juice, her face screwed up with the effort. Tatiana was, as always, sitting beside her but not looking at her, and suddenly her eyes went wide. She put her hand right below her sternum, and then she uttered one small word that suggested a world of possibility: “Whoa!”

New York Times Magazine: Could Conjoined Twins Share a Mind?

(Thanks Trevor)

Is Punning a Disease?

April 18, 2012 / Klint Finley

Last year author Douglas Coupland predicted that within the next 10 years: “We will still be annoyed by people who pun, but we will be able to show them mercy because punning will be revealed to be some sort of connectopathic glitch: The punner, like someone with Tourette’s, has no medical ability not to pun.”

Turns out some researchers already think “bad humor,” including excessive punning, is a disease. MSNBC reports:

Witzelsucht (the Germans just have the best words for everything, don’t they?) is a brain dysfunction that causes all sorts of compulsive silliness: bad jokes, corny puns, wacky behavior. It’s also sometimes called the “joking disease,” and as Taiwanese researchers phrased it in a 2005 report, it’s a “tendency to tell inappropriate and poor jokes.” We’ve covered all sorts of strange disorders of the mind in earlier Body Odd posts: one disorder makes you believe your loved ones are strangers, another convinces you that your hand has taken on a life of its own. Now, we give you a brain disorder that actually causes a poor sense of humor.

MSNBC: No pun intended: ‘Joking disease’ is no joke

The Great Adderall Shortage

February 29, 2012 / Klint Finley

Kelly Bourdet writes for Vice Motherboard:

To prevent hoarding of materials and their potential for theft and illicit use, the Drug Enforcement Agency sets quotas for the chemical precursors to drugs like Adderall. The DEA projects the need for amphetamine salts, then produces and distributes the materials to pharmaceutical companies so that they can produce their drugs. But with the number of prescriptions for Adderall jumping 13 percent in the past year, pharmaceutical companies claim that the quotas are no longer sufficient for supplying Americans with their Adderall.

I hadn’t realized that it wasn’t known how these drugs work:

Despite the millions of prescriptions written each year for ADHD, the scientific community isn’t entirely in agreement on how these drugs actually work. Ritalin increases focus and energy through inhibiting the re-uptake of both dopamine and norepinephrine in the brain. These neurotransmitters then remain in the synapse longer, and their effects are felt in the form of heightened focus and awareness. Adderall, however, works via a slightly different mechanism. While it’s postulated that Adderall also inhibits the re-uptake of these same neurotransmitters, amphetamines also trigger the release of dopamine. This affects the brain’s reward mechanisms, so it’s not only easier to focus on mundane or repetitive tasks, it can also feel positively delightful to do so.

Motherboard: Anatomy of the Great Adderall Drought

The article also goes into some of the shadier aspects of the shortage – such as Shire’s missed shipments to competitors and the creation of its newer, more expensive alternative Vyvanse.

Why so much demand? From a recent Portland Tribune article:

Ritalin and Adderol are commonly prescribed for attention deficit disorder. But a recent study showed that as many as one in four students at an Ivy League university were using one of the two not because they had a diagnosis, but because it helped them study.

And it’s not just the students:

“I’ve had several colleagues say to me, ‘You’re a stupid guy if you’re not using Ritalin to stay up all night.’ You’re much more productive, your career takes off much faster,” says Paul Zak, director of the Center for Neuroeconomic Studies at Claremont Graduate University in California.

Zak isn’t sure that those Ivy League students and his college professor colleagues are doing anything wrong.

“I’m very conflicted,” he says.

And, on the subject Adderall, here’s an interesting paper: When we enhance cognition with Adderall, do we sacrifice creativity? A preliminary study. The study concluded that Adderall might actually improve creativity for those who score poorly on tests of creativity (for some background on creativity testing see here).

How and Why Exercise Boosts Your Brain. Plus: How Little Exercise Can You Get By With?

February 22, 2012 / Klint Finley

The New York Times on how exercise raises the level of glycogen available to the brain:

After the single session on the treadmill, the animals were allowed to rest and feed, and then their brain glycogen levels were studied. The food, it appeared, had gone directly to their heads; their brain levels of glycogen not only had been restored to what they had been before the workout, but had soared past that point, increasing by as much as a 60 percent in the frontal cortex and hippocampus and slightly less in other parts of the brain. The astrocytes had “overcompensated,” resulting in a kind of brain carbo-loading.

The levels, however, had dropped back to normal within about 24 hours.

That was not the case, though, if the animals continued to exercise. In those rats that ran for four weeks, the “supercompensation” became the new normal, with their baseline levels of glycogen showing substantial increases compared with the sedentary animals. The increases were especially notable in, again, those portions of the brain critical to learning and memory formation — the cortex and the hippocampus.

New York Times: How Exercise Fuels the Brain

Also:

While many of us wonder just how much exercise we really need in order to gain health and fitness, a group of scientists in Canada are turning that issue on its head and asking, how little exercise do we need?

The emerging and engaging answer appears to be, a lot less than most of us think — provided we’re willing to work a bit. […]

For years, the American Heart Association and other organizations have recommended that people complete 30 minutes or more of continuous, moderate-intensity exercise, such as a brisk walk, five times a week, for overall good health.

But millions of Americans don’t engage in that much moderate exercise, if they complete any at all. Asked why, a majority of respondents, in survey after survey, say, “I don’t have time.”

Intervals, however, require little time. They are, by definition, short. But whether most people can tolerate intervals, and whether, in turn, intervals provide the same health and fitness benefits as longer, more moderate endurance exercise are issues that haven’t been much investigated.

New York Times: How 1-Minute Intervals Can Improve Your Health

(via socialphysicist)

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