Biopunk Archives | Page 4 of 11

TagBiopunk

Hungary detains 4 over illegal stem cell treatment

August 2, 2009 / Klint Finley

Hungarian police have detained four people on suspicion of carrying out illegal, untested stem cell treatments using embryos or aborted fetuses at a Hungarian private clinic, police said in a statement.

The statement, posted on the official police website www.police.hu late on Tuesday, said the suspects — two Hungarians, one U.S. and one Ukrainian citizen — were detained on July 27 just as they were preparing to treat a new patient.

Police said they launched a procedure on “suspicion of a banned use of the human body.”

Reuters: Hungary detains 4 over illegal stem cell treatment

R.U. Sirius notes this may be the first ever stem cell bust.

Researchers rapidly turn E. coli into biotech factories

July 29, 2009 / Klint Finley

High-throughput sequencing has turned biologists into voracious genome readers, enabling them to scan millions of DNA letters, or bases, per hour. When revising a genome, however, they struggle, suffering from serious writer’s block, exacerbated by outdated cell programming technology. Labs get bogged down with particular DNA sentences, tinkering at times with subsections of a single gene ad nauseam before moving along to the next one.

A team has finally overcome this obstacle by developing a new cell programming method called Multiplex Automated Genome Engineering (MAGE). Published online in Nature on July 26, the platform promises to give biotechnology, in particular synthetic biology, a powerful boost.

Led by a pair of researchers in the lab of Harvard Medical School Professor of Genetics George Church, the team rapidly refined the design of a bacterium by editing multiple genes in parallel instead of targeting one gene at a time. They transformed self-serving E. coli cells into efficient factories that produce a desired compound, accomplishing in just three days a feat that would take most biotech companies months or years.

PhysOrg: Researchers rapidly turn bacteria into biotech factories

(Thanks Nova)

Botox Parties, Michael Jackson, and the Disillusioned Transhumanist

July 1, 2009 / Klint Finley

Yet when I asked a lot of “average” people — people who weren’t part of my circle — what they would do with the kind of self-transformative power that may perhaps be ours to wield, I was increasingly appalled. The jocks I talked to wanted to be bigger and stronger so they could beat the shit out of everybody else; the women wanted to morph into their ideal role models. I began to realize that what most people wanted was conformity; their “ideals” would turn us into a world of underachieving Nicole Kidmans and eight-foot Brad Pitts, identical cut-outs with no individualism.

My previous rather naive notion that biotechnology would free us from the tyranny of “normalcy,” that we could become anything we wanted, morph ourselves into elongated, blue-skinned, orange-haired, sixteen-fingered geniuses or perhaps flying ribbons of sensual bliss that performed acrobatic choreographies above the sunset, was a very utopian and, as it turns out, unpopular dream. Individuality or creative improvisation is the last thing most people want. So Botox is really a dreadful symptom of a new, radical mundanity enabled by biotechnology. And that’s disillusioning.

H+: Botox Parties, Michael Jackson, and the Disillusioned Transhumanist

Smart drugs article from the New Yorker

May 22, 2009 / Klint Finley

This has been in my virtual “to read” pile for a long time. It’s more interesting than I expected.

If we eventually decide that neuroenhancers work, and are basically safe, will we one day enforce their use? Lawmakers might compel certain workers—emergency-room doctors, air-traffic controllers—to take them. (Indeed, the Air Force already makes modafinil available to pilots embarking on long missions.)

New Yorker: The underground world of “neuroenhancing” drugs.

I tried piracetam in college, but between the cost (I had to order it from Biogenesis Labs and the way it made my stomach feel, I didn’t think it was worth the slight boost.

I have found that Biotest Laboratory’s Spike is an effective “cognitive enhancer,” however. I used it during both Esozones to keep alert and productive on very little sleep under high pressure circumstances. You used to be able to buy it at GNC, but it seems they don’t carry it any more. You can still buy it online. I didn’t find the energy drink they market to be as effective as the pills.

Spike’s “secret sauce” is “thiamine di(2-methylpropionate) disulfide.” It sounds fancy, and they make an effort to make it appear they have something new and exclusive, but it’s really just a chemical name for sulbutiamine, which has been around since the classic Smart Drugs book and was reviewed in Mondo 2000.

Although it’s old, by no means do I consider this product “safe” – use at your own risk.

In Attics and Closets, ‘Biohackers’ Discover Their Inner Frankenstein

May 15, 2009 / Klint Finley

In Massachusetts, a young woman makes genetically modified E. coli in a closet she converted into a home lab. A part-time DJ in Berkeley, Calif., works in his attic to cultivate viruses extracted from sewage. In Seattle, a grad-school dropout wants to breed algae in a personal biology lab.

These hobbyists represent a growing strain of geekdom known as biohacking, in which do-it-yourselfers tinker with the building blocks of life in the comfort of their own homes. Some of them buy DNA online, then fiddle with it in hopes of curing diseases or finding new biofuels.

But are biohackers a threat to national security? […]

The man on the other end of the line was Nils Gilman, a researcher with Monitor 360, a San Francisco company that provides “geo-strategic” research. Mr. Gilman declined to identify his client, saying only that it’s a branch of the U.S. government involved in biosecurity. “I think they want to know, is this something we need to worry about?” he said — particularly, could the biohackers’ gadgets and methods, in the wrong hands, create dangerous pathogens?

Wall Street Journal: In Attics and Closets, ‘Biohackers’ Discover Their Inner Frankenstein

Bad Times Spur Entrepreneurship, But There’s a Catch

March 16, 2009 / Klint Finley

Dan Gilmore guest post at BB:

That’s great. Except for one thing, which the article completely misses: You won’t find too many people in their middle ages or older in this category. Why? Because they can’t get health insurance. America’s health-care system makes it all but impossible for an older worker to try something new.

Even younger startup owners who are relatively healthy and have insurance are just a half-step from disaster. The insurance industry is in the business of not paying claims whenever possible, after all, and health insurers are working hardest to find ways not to cover people who might get sick even as they deny as many claims as possible from people who’ve been paying premiums.

The day we have national health care is the day that we unleash a wave of entrepreneurship the likes of which we’ve never seen before. That’s one of the best reasons for moving toward such a system.

Full Story: Boing Boing

Designer babies are here? Nope.

March 3, 2009 / Klint Finley

You know what I’m sick of? Bullshit medical “journalism”.

Where some fucking doctor in LA tries to hype up his IVF clinic by calling it a designer baby factory; just so that when Paris cunting Hilton decides it’s time to procreate, and thusly have her indentured servant carry the perfect anti-Christ to term, she’ll look this guy up.

So he puts out a press-release.

And the BBC picks it up and gets blue-sky quotes from Dr Gillian Lockwood, a “UK fertility expert” and member of the “Royal College of Obstetricians and Gynaecologists’ ethics committee” […]

China didn’t need any fancy tech to get a roughly 20million strong population gap between males and females. They just threw out the girls.

Selection isn’t the same thing as design. Sure, it’s good to talk and workshop future ethical scenarios, but don’t make that the focus of your story. Please. Because when we actually can design life, blue eyes will be the last thing anyone will be asking for. Or, it will be the most boring thing, anyway.

You can worry about the missing green-eyed, I’ll be asking for a chameleon DNA-splice.

Full Story: Grinding

How to build your own algae reactors

February 6, 2009 / Klint Finley

algae bioreactor

So I wanted to put together a simple example of a bio reactor using simple off the shelf parts and aquarium parts available from nearly any big chain store to make a simple reactor on the cheap. This is the most basic algae reactor design overall and while I used some glass containers for my reactor other ideal containers would be an empty 2 leader bottle or plastic milk jug. This design is really perfect for backup cultures or to keep unique strings of algae’s to start larger reactors off. Using simple off the shelf parts and aquarium parts available from nearly any big chain store these days you can make this simple reactor on the cheap.

Instructions and more projects: AlgaeGeek

(via Grinding)

Amateurs are trying genetic engineering at home

December 26, 2008 / Klint Finley

he Apple computer was invented in a garage. Same with the Google search engine. Now, tinkerers are working at home with the basic building blocks of life itself.

Using homemade lab equipment and the wealth of scientific knowledge available online, these hobbyists are trying to create new life forms through genetic engineering — a field long dominated by Ph.D.s toiling in university and corporate laboratories.

In her San Francisco dining room lab, for example, 31-year-old computer programmer Meredith L. Patterson is trying to develop genetically altered yogurt bacteria that will glow green to signal the presence of melamine, the chemical that turned Chinese-made baby formula and pet food deadly. […]

Co-founder Mackenzie Cowell, a 24-year-old who majored in biology in college, said amateurs will probably pursue serious work such as new vaccines and super-efficient biofuels, but they might also try, for example, to use squid genes to create tattoos that glow.

Cowell said such unfettered creativity could produce important discoveries.

“We should try to make science more sexy and more fun and more like a game,” he said.

Full Story: AP

(via Cryptogon)

Potential AIDS cure?

November 11, 2008 / Klint Finley

The startling case of an AIDS patient who underwent a bone marrow transplant to treat leukemia is stirring new hope that gene-therapy strategies on the far edges of AIDS research might someday cure the disease.

The patient, a 42-year-old American living in Berlin, is still recovering from his leukemia therapy, but he appears to have won his battle with AIDS. Doctors have not been able to detect the virus in his blood for more than 600 days, despite his having ceased all conventional AIDS medication. Normally when a patient stops taking AIDS drugs, the virus stampedes through the body within weeks, or days.

“I was very surprised,” said the doctor, Gero Hütter.

The breakthrough appears to be that Dr. Hütter, a soft-spoken hematologist who isn’t an AIDS specialist, deliberately replaced the patient’s bone marrow cells with those from a donor who has a naturally occurring genetic mutation that renders his cells immune to almost all strains of HIV, the virus that causes AIDS.

Full Story: Wall Street Journal