A drug that could give you perfect visual memory

RGS-14

Imagine if you could look at something once and remember it forever. You would never have to ask for directions again. Now a group of scientists has isolated a protein that mega-boosts your ability to remember what you see.

A group of Spanish researchers reported today in Science that they may have stumbled upon a substance that could become the ultimate memory-enhancer. The group was studying a poorly-understood region of the visual cortex. They found that if they boosted production of a protein called RGS-14 (pictured) in that area of the visual cortex in mice, it dramatically affected the animals’ ability to remember objects they had seen.

io9: A drug that could give you perfect visual memory

(via Edge of Tomorrow)

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Ritalin boosts learning by increasing brain plasticity

Ritalin

Doctors treat millions of children with Ritalin every year to improve their ability to focus on tasks, but scientists now report that Ritalin also directly enhances the speed of learning.

In animal research, the scientists showed for the first time that Ritalin boosts both of these cognitive abilities by increasing the activity of the neurotransmitter dopamine deep inside the brain. Neurotransmitters are the chemical messengers neurons use to communicate with each other. They release the molecule, which then docks onto receptors of other neurons. The research demonstrated that one type of dopamine receptor aids the ability to focus, and another type improves the learning itself.

The scientists also established that Ritalin produces these effects by enhancing brain plasticity – strengthening communication between neurons where they meet at the synapse. Research in this field has accelerated as scientists have recognized that our brains can continue to form new connections – remain plastic – throughout life.

PhysOrg: Ritalin boosts learning by increasing brain plasticity

(via Chris S.)

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Universities told to consider testing for smart drugs

smart drugs

Universities must investigate measures, including random dope testing, to tackle the increasing use of cognitive enhancment drugs by students for exams, a leading behavioural neuro­scientist warns.

Student use of drugs, such as Ritalin and modafinil, available over the internet and used to increase the brain’s alertness, had “enormous implications for universities”, said Barbara Sahakian, a professor of clinical neuropsychology at Cambridge University’s psychiatry department.

Normally prescribed for neurological disorders including Alzheimer’s disease, attention deficit hyperactivity disorder (ADHD) and narcolepsy, such drugs boost acetylcholine in the brain, improving alertness and attention. Their use has prompted concerns that they could give students an unfair advantage. “This is something that universities really have to discuss. They should have some strategy, some kind of active policy,” Sahakian said.

Guardian: Universities told to consider dope tests as student use of ’smart drugs’ soars

(via h+)

Previous look at smart drugs here at Technoccult

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Smart drugs article from the New Yorker

This has been in my virtual “to read” pile for a long time. It’s more interesting than I expected.

If we eventually decide that neuroenhancers work, and are basically safe, will we one day enforce their use? Lawmakers might compel certain workers—emergency-room doctors, air-traffic controllers—to take them. (Indeed, the Air Force already makes modafinil available to pilots embarking on long missions.)

New Yorker: The underground world of “neuroenhancing” drugs.

I tried piracetam in college, but between the cost (I had to order it from Biogenesis Labs and the way it made my stomach feel, I didn’t think it was worth the slight boost.

I have found that Biotest Laboratory’s Spike is an effective “cognitive enhancer,” however. I used it during both Esozones to keep alert and productive on very little sleep under high pressure circumstances. You used to be able to buy it at GNC, but it seems they don’t carry it any more. You can still buy it online. I didn’t find the energy drink they market to be as effective as the pills.

Spike’s “secret sauce” is “thiamine di(2-methylpropionate) disulfide.” It sounds fancy, and they make an effort to make it appear they have something new and exclusive, but it’s really just a chemical name for sulbutiamine, which has been around since the classic Smart Drugs book and was reviewed in Mondo 2000.

Although it’s old, by no means do I consider this product “safe” – use at your own risk.

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How to add 1 billion points to the global I.Q. cheaply and easily

Almost one-third of the world’s people don’t get enough iodine from food and water. The result in extreme cases is large goiters that swell their necks, or other obvious impairments such as dwarfism or cretinism. But far more common is mental slowness.

When a pregnant woman doesn’t have enough iodine in her body, her child may suffer irreversible brain damage and could have an I.Q. that is 10 to 15 points lower than it would otherwise be. An educated guess is that iodine deficiency results in a needless loss of more than 1 billion I.Q. points around the world. [...]

“Probably no other technology,” the World Bank said of micronutrients, “offers as large an opportunity to improve lives … at such low cost and in such a short time.”

Yet the strategy hasn’t been fully put in place, partly because micronutrients have zero glamour. There are no starlets embracing iodine. And guess which country has taken the lead in this area by sponsoring the Micronutrient Initiative? Hint: It’s earnest and dull, just like micronutrients themselves.

Ta-da — Canada!

Full Story: New York Times

(Thanks Justin)

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