A drug that could give you perfect visual memory

RGS-14

Imagine if you could look at something once and remember it forever. You would never have to ask for directions again. Now a group of scientists has isolated a protein that mega-boosts your ability to remember what you see.

A group of Spanish researchers reported today in Science that they may have stumbled upon a substance that could become the ultimate memory-enhancer. The group was studying a poorly-understood region of the visual cortex. They found that if they boosted production of a protein called RGS-14 (pictured) in that area of the visual cortex in mice, it dramatically affected the animals’ ability to remember objects they had seen.

io9: A drug that could give you perfect visual memory

(via Edge of Tomorrow)

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Electro-shock experiment replicated in France

French torture TV show

A French TV documentary features people in a spoof game show administering what they are told are near lethal electric shocks to rival contestants.

Those taking part are told to pull levers to inflict shocks – increasing in voltage – upon their opponents.

Although unaware that the contestants were actors and there was no electrical current, 82% of participants in the Game of Death agreed to pull the lever.

Programme makers say they wanted to expose the dangers of reality TV shows.

They say the documentary shows how many participants in the setting of a TV show will agree to act against their own principles or moral codes when ordered to do something extreme.

BBC: French TV contestants made to inflict ‘torture’

This is, of course, a replication of the Milgram experiment.

Glenn Greenwald notes the irony of Fox News’s moral outrage over the incident.

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700-year-old Brain Found Preserved

700 year old preserved brain

ResearchBlogging.orgEvolutionary psychology tends to receive harsh criticism, and often rightly so. One of the main reasons for this is the severe lack of evidence for many of it’s proposals given that the paucity of fossilised brains fails to bolster many a case. And it isn’t even anyone’s fault. That’s just the way it goes sometimes, that the brain is a jelly-like substance that is subject to decay after death, and there’s no way we can objectively analyse or verify any differences in brains of long ago with brains of today.

This isn’t set to change anytime soon, but the remarkable discovery of a medieval child’s brain was the subject of a Neuroimage paper published recently. This is extremely exciting on many counts: the brain has been so fantastically preserved that it is possible to identify the frontal, temporal and occipital lobes, and even the sulci and gyri, the grooves and furrows channeled into brains.

However it is only the left-hemisphere that survived and not the entire brain, which had also shrunk to about 80% of it’s original weight due to the (natural) mummification process.

Neurowhoa: 700-year-old Brain Found Preserved

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Brain Naturally Follows Scientific Method

Brain naturally follows scientific method

It turns out that there is a striking similarity between how the human brain determines what is going on in the outside world and the job of scientists. Good science involves formulating a hypothesis and testing whether this hypothesis is compatible with the scientist’s observations. Researchers in the Max Planck Institute for Brain Research in Frankfurt together with the University of Glasgow have shown that this is what the brain does as well. A study shows that it takes less effort for the brain to register predictable as compared to unpredictable images.

Alink and colleagues based this conclusion on the characteristics of responses in the primary visual cortex. It is known that the primary visual cortex is critical for vision and that responses in this brain area create a map of what we are currently looking at. Alink and colleagues, however, for the first time show that images induce smaller responses in this area when they are predictable. The implication of this finding is that the brain does not just sit and wait for visual signals to arrive. Instead, it actively tries to predict these signals and when it is right it is rewarded by being able to respond more efficiently. If it is wrong, massive responses are required to find out why it is wrong and to come up with better predictions.

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Psychopaths’ Brains Wired to Seek Rewards, No Matter the Consequences

Psychopath

The brains of psychopaths appear to be wired to keep seeking a reward at any cost, new research from Vanderbilt University finds. The research uncovers the role of the brain’s reward system in psychopathy and opens a new area of study for understanding what drives these individuals.

“This study underscores the importance of neurological research as it relates to behavior,” Dr. Francis S. Collins, director of the National Institutes of Health, said. “The findings may help us find new ways to intervene before a personality trait becomes antisocial behavior.”

The results were published March 14, 2010, in Nature Neuroscience.

Science Daily: Psychopaths’ Brains Wired to Seek Rewards, No Matter the Consequences

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Different parts process deliberately recalled and spontaneously triggered memories

Photography, memory, and mental models by Kevin Dooley

The studies in Kristiina Kompus’s dissertation show that these two different ways of remembering things are initiated by entirely different signal paths in the brain. Efforts to retrieve a specific memory are dealt with by the upper part of the frontal lobe. This area of the brain is activated not only in connection with memory-related efforts but also in all types of mental efforts and intentions, according to the dissertation. This part of the brain is not involved in the beginning of the process of unintentionally remembering something as a response to external stimuli. Instead, such memories are activated by specific signals from other parts of the brain, namely those that deal with perceived stimuli like smells, pictures, and words. Sometimes such memories are thought to be more vivid and emotional; otherwise they would not be activated in this way. But Kristiina Kompus’s dissertation shows that this is not the case — memories do not need to be emotionally charged to be revived spontaneously, unintentionally. Nor do memories that are revived spontaneously activate the brain more than other memories.

Science Daily: Different Signal Paths for Spontaneous and Deliberate Activation of Memories

(Photo credit: Kevin Dooley / CC)

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Neanderthals Not Dumb, but Made Dull Gadgets

blades and flakes

After analyzing tools used by Neanderthals, British and American archaeologists say they were just as well-crafted as those used by our ancestors.

Flakes — wide-bodied stones used for cutting by Neanderthals and Homo sapiens — are just as useful, if not moreso, than narrow stone blades later favored by modern humans, who charged out of Africa 50,000 years ago and soon replaced their larger, hairier European forerunners.

“It’s not a better technology, it’s just a different technology,” said Metin Eren, a University of Exeter experimental archaeology student. [...]

The superiority of blades has long been seen as evidence of human superiority. But according to Eren’s team, blades had only one advantage: they can be easily attached to shafts.

Wired Science: Neanderthals Not Dumb, but Made Dull Gadgets

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Your Computer Really Is a Part of You

Heidegger schematic

The findings come from a deceptively simple study of people using a computer mouse rigged to malfunction. The resulting disruption in attention wasn’t superficial. It seemingly extended to the very roots of cognition.

“The person and the various parts of their brain and the mouse and the monitor are so tightly intertwined that they’re just one thing,” said Anthony Chemero, a cognitive scientist at Franklin & Marshall College. “The tool isn’t separate from you. It’s part of you.”

Chemero’s experiment, published March 9 in Public Library of Science, was designed to test one of Heidegger’s fundamental concepts: that people don’t notice familiar, functional tools, but instead “see through” them to a task at hand, for precisely the same reasons that one doesn’t think of one’s fingers while tying shoelaces. The tools are us.

This idea, called “ready-to-hand,” has influenced artificial intelligence and cognitive science research, but without being directly tested.

Wired Science: Your Computer Really Is a Part of You

(via Cole Tucker)

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Intendix Brain-Computer Interface goes commercial

Intendix

The world’s first patient-ready and commercially available brain computer interface just arrived at CeBIT 2010. The Intendix from Guger Technologies (g*tec) is a system that uses an EEG cap to measure brain activity in order to let you type with your thoughts. Meant to work with those with locked-in syndrome, or other disabilities, Intendix is simple enough to use after just 10 minutes of training. You simply focus on a grid of letters as they flash. When your desired letter lights up, brain activity spikes and Intendix types it. As users master the system, a few will be able to type as quickly as 1 letter a second. Besides typing, it can also trigger alarms, convert text to speech, print, copy, or email. Retailing for €9000 (~$12,250), Intendix isn’t cheap, but it’s the first thought to type system available that’s geared towards easy to setup personal use in the home. Brain computer interfaces just got more accessible, and that’s a step towards them becoming more common all over the world.

Singularity Hub: Intendix, The Brain Computer Interface Goes Commercial

(via Edge of Tomorrow)

See also:

Chris Arkenberg’s 3 Scenarios for Brain Computer Interface.

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Life Without Serotonin

serotonin Life Without Serotonin

I had no idea the link between serotonin and depression was in doubt. Very interesting:

Via Dormivigilia, I came across a fascinating paper about a man who suffered from a severe lack of monoamine neurotransmitters (dopamine, serotonin etc.) as a result of a genetic mutation. [...]

Overall, though, the biggest finding here was a non-finding: this patient wasn’t depressed, despite having much reduced serotonin levels. This is further evidence that serotonin isn’t the “happy chemical” in any simple sense.

On the other hand, the similarities between his symptoms and some of the symptoms of depression suggest that serotonin is doing something in that disorder. This fits with existing evidence from tryptophan depletion studies showing that low serotonin doesn’t cause depression in most people, but does re-activate symptoms in people with a history of the disease. As I said, it’s complicated…

Neuroskeptic: Life Without Serotonin

See also:

Serotonin and Depression: A Disconnect between the Advertisements and the Scientific Literature

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Evolutionary, algorithmic & generative design round-up

Michael Piasecki's Cellular Bowl

Shapeways has a round-up of evolutionary, algorithmic & generative design projects, including the “cellular bowl” above, designed with Processing.

The marriage of tech and design is all around us. In a world where everything is designed a meta “way to design” that algorithmically cuts through the clutter is very appealing. A perfect design algorithm could potentially engender choice in design the same way that Google’s PageRank set of algorithms do for the web. And this is what generative design already partially does. It simplifies design by codifying it and somewhere within lies the promise of “true”, “simple” & “beautiful” design.

With technologies such as 3D printing letting everyone design or co-design things there is also a real need for generative tools. They allow for unique designs but since each is machine made, the marriage is a conceptually comfortable and inexpensive one. Also, rather than forcing the customer into a “blank canvas conundrum” whereby the sheer possibility overwhelms them to the point inactivity, generated models could lead to choice or guided choice in design.

Shapeways: Dasign: data driven, evolutionary, algorithmic & generative design

(via Bruce Sterling)

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Ritalin boosts learning by increasing brain plasticity

Ritalin

Doctors treat millions of children with Ritalin every year to improve their ability to focus on tasks, but scientists now report that Ritalin also directly enhances the speed of learning.

In animal research, the scientists showed for the first time that Ritalin boosts both of these cognitive abilities by increasing the activity of the neurotransmitter dopamine deep inside the brain. Neurotransmitters are the chemical messengers neurons use to communicate with each other. They release the molecule, which then docks onto receptors of other neurons. The research demonstrated that one type of dopamine receptor aids the ability to focus, and another type improves the learning itself.

The scientists also established that Ritalin produces these effects by enhancing brain plasticity – strengthening communication between neurons where they meet at the synapse. Research in this field has accelerated as scientists have recognized that our brains can continue to form new connections – remain plastic – throughout life.

PhysOrg: Ritalin boosts learning by increasing brain plasticity

(via Chris S.)

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One in four Germans wants microchip under skin

RFID Implant

Above: Amal Graafstra’s self-administered RFID implant.

It sounds like something from a sci-fi film, but one in four Germans would be happy to have a microchip implanted in their body if they derived concrete benefits from it, a poll Monday showed. [...]

In all, 23 percent of around 1,000 respondents in the survey said they would be prepared to have a chip inserted under their skin “for certain benefits”.

Around one in six (16 percent) said they would wear an implant to allow emergency services to rescue them more quickly in the event of a fire or accident.

And five percent of people said they would be prepared to have an implant to make their shopping go more smoothly.

PhysOrg: One in four Germans wants microchip under skin: poll

(via Chris S.)

See also:

Scrapheap Transhumanism

Lepht Anonym’s blog

Amal Graafstra’s blog

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Flat Earth Society president interviewed by the Guardian

Flat Earth

Daniel Shenton should be the most irrational man in the world. As the new president of the Flat Earth Society, you’d imagine he would also think that evolution is a scam and global warming a myth. He should ­argue that smoking does not cause cancer and HIV does not lead to Aids.

Yes, that Flat Earth Society, a group that has become a living metaphor for backward thinking and a refusal to face scientific facts. Yes, it is still going, and no, this isn’t an early April fool.

In fact, Shenton turns out to have resolutely mainstream views on most issues. The 33-year-old American, originally from Virginia but now living and working in London, is happy with the work of Charles Darwin. He thinks the evidence for man-made global warming is strong, and he dismisses suggestions that his own government was involved with the 9/11 terrorist attacks.

He is mainstream on most issues, but not all. For when Shenton rides his motorbike, he says it is not gravity that pins him to the road, but the rapid upward motion of a disc-shaped planet. Countries, according to him, spread across this flat world as they appear to do on a map, with Antarctica as a ring of mountains strung around the edge. And, yes, you can fall off.

Guardian: The Earth is flat? What planet is he on?

(Thanks Paul)

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Atheists are disagreeable and unconscientious?

Atheist personality

Atheists may be smarter, but are we also disagreeable? (Well, this guy may be).

A new analysis comparing the personalities of religious and less religious people has found that religiosity is generally linked to agreeableness and conscientiousness. Well, that’s the headline. To understand why this might be, you need to dig into the details of the study. [...]

The five-factor model is the most widely used measure of personality. According to this model, individuals can be defined according to where they lie on one of five scales: extroversion, agreeableness, conscientiousness, neuroticism, and openness.

One consistent finding stood out: across all measures of religion, cultural areas, and age groups, people who scored higher on agreeableness and conscientiousness also reported being more religious.

Epiphenom: Atheists are disagreeable and unconscientious

There’s also the whole problem relying on personality testing to begin with.

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Are There Really ‘Continents’ of Floating Garbage?

Trash patterns

Plastic ocean trash

Since stories have started surfacing more recently, many have wondered, if the rumors are true. Are there really ‘continents’, or massive floating garbage patches residing in the pacific ocean? Apparently, the rumors are true, and these unsightly patches are reportedly killing marine life and releasing poisons that enter the human food chain, as well. However, before you start imagining a plastic version of Maui, keep in mind that these plastic patches certainly aren’tsolid surfaced islands that you could build a house on! Ocean currents have collected massive amounts of garbage into a sort of plastic “soup” where countless bits of discarded plastic float intertwined just beneath the surface. Indeed, the human race has really made its mark. One enormous plastic patch is estimated to weigh over 3 million tons altogether and cover an area roughly twice the size of Texas.

Daily Galaxy: Are There Really ‘Continents’ of Floating Garbage?

(via Atom Jack)

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Seven theories of everything

Theories of Everything

The “theory of everything” is one of the most cherished dreams of science. If it is ever discovered, it will describe the workings of the universe at the most fundamental level and thus encompass our entire understanding of nature. It would also answer such enduring puzzles as what dark matter is, the reason time flows in only one direction and how gravity works. Small wonder that Stephen Hawking famously said that such a theory would be “the ultimate triumph of human reason – for then we should know the mind of God”.

But theologians needn’t lose too much sleep just yet. Despite decades of effort, progress has been slow. Rather than one or two rival theories whose merits can be judged against the evidence, there is a profusion of candidates and precious few clues as to which (if any) might turn out to be correct.

Here’s a brief guide to some of the front runners.

The theories they summarize:

-String theory
-Loop quantum gravity
-CDT
-Quantum Einstein gravity
-Quantum graphity
-Internal relativity
-E8

New Scientist: Seven theories of everything

(via Wade)

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Open source “god helmet” project

Cosmic Eye

The project is in a very early alpha stage. Some of the current goals for the project include:

-Create a workable and easy to build hardware design to allow experimentation similar to that done by Dr. Persinger.

-Develop firmware for any integrated controllers

-Develop software that facilitates controlled application of TMS or rTMS utilizing the hardware

-Software integration with openEEG and Sbagen for a rich experimental environment

Open-rTMS Project

(via William Gibson)

(Photo Credit: h.koppdelaney’s / CC)

See also:

The God Experiments

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Did a coronal mass ejection cause the Chile earthquake?

Coronal mass ejection

Above: image of the coronal mass ejection on February 26th, 2010 from NASA

Van’s Hardware Journal points out that the 2010 Chile earthquake was preceded by a Coronal mass ejection.

(via Fadereu)

Space.com’s FAQ states “The question of a solar disturbance/magnetic field change related to earthquakes has been thoroughly investigated and found to be unproven,” and cites the conclusions of a 1996 conference on the subject.

However, Russian and Chinese scientists continue to study the possibility of a connection.

As you’ve probably already heard, this earthquake altered the axis of the earth. So, if it IS true that this earthquake was caused by the sun (and I’m not saying that it was), that means that the sun actually caused a change in the earth’s axis.

See also: Reza Negarestani work such as Cyclonopedia.

(My noise art piece “Thirst for Annihilation” from my album Return to the Wasteland was created using NASA’s recording of radio interference caused by sunspots, inspired by Negarestani’s work and named after a book, which I have not read, by his collaborator Nick Land)

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Backpack Hydroelectric Generator Gives You 500 Watts on the Move

Backpack Hydroelectric Plant

Just a prototype, for now:

A human-portable hydroelectric generator that weighs about 30 pounds and generates 500 watts of power may soon be a new option for off-grid power.

Developed by Bourne Energy of Mailbu, California, the Backpack Power Plant can create clean, quiet power from any stream deeper than 4 feet.

Backpack Hydroelectric Plant Gives You 500 Watts on the Move

Beats the heck out of expensive leaky nuclear power plants any day.

(via Atom Jack)

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Is Your Brain A Communist?

Communist Brain

Kind of. The article, Neural evidence for inequality-averse social preferences, doesn’t mention the C word, but it does claim to have found evidence that people’s brains display more egalitarianism than people themselves admit to. [...]

When people received money for themselves, activity in the ventromedial prefrontal cortex (vmPFC) and the ventral striatum correlated with the size of their gain.

However, when presented with a payment to the other person, these areas seemed to be rather egalitarian. Activity rose in rich people when their poor colleagues got money. In fact, it was greater in that case than when they got money themselves, which means the “rich” people’s neural activity was more egalitarian than their subjective ratings were. Whereas in “poor” people, the vmPFC and the ventral striatum only responded to getting money, not to seeing the rich getting even richer.

The authors of the study concluded that this is evidence of a neurobiological preference against inequality.

NeuroSkeptic: Is Your Brain A Communist?

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Deep-Sea Bacteria Form Avatar-Style Electrochemical Networks

network Deep Sea Bacteria Form Avatar Style Electrochemical Networks

According to findings that could have been pulled from a deep-sea sequel to Avatar, bacteria appear to conduct electrical currents across the ocean floor, driving linked chemical reactions at relatively vast distances.

Noticed only when reseachers happened to test sediment leftovers from another experiment, the phenomenon may add a new mechanism to Earth’s biogeochemistry.

Wired Science: Deep-Sea Bacteria Form Avatar-Style Electrochemical Networks

(via Atom Jack)

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Skinput turns your arm into a touchscreen

Skinput

In Skinput, a keyboard, menu, or other graphics are beamed onto a user’s palm and forearm from a pico projector embedded in an armband. An acoustic detector in the armband then determines which part of the display is activated by the user’s touch. As the researchers explain, variations in bone density, size, and mass, as well as filtering effects from soft tissues and joints, mean different skin locations are acoustically distinct. Their software matches sound frequencies to specific skin locations, allowing the system to determine which “skin button” the user pressed.

Read More -PhysOrg: Skinput turns your arm into a touchscreen

(via Edge of Tomorrow)

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Pot smokers who started young more likely to exhibit psychosis

Pot smoker

Among all the participants, a longer duration since the first time they used cannabis was associated with multiple psychosis-related outcomes. “Compared with those who had never used cannabis, young adults who had six or more years since first use of cannabis (i.e., who commenced use when around 15 years or younger) were twice as likely to develop a non-affective psychosis and were four times as likely to have high scores on the Peters et al Delusions Inventory [a measure of delusion],” the authors write. “There was a ‘dose-response’ relationship between the variables of interest: the longer the duration since first cannabis use, the higher the risk of psychosis-related outcomes.”

However:

“The nature of the relationship between psychosis and cannabis use is by no means simple,” they write. Individuals who had experienced hallucinations early in life were more likely to have used cannabis longer and to use it more frequently. “This demonstrates the complexity of the relationship: those individuals who were vulnerable to psychosis (i.e., those who had isolated psychotic symptoms) were more likely to commence cannabis use, which could then subsequently contribute to an increased risk of conversion to a non-affective psychotic disorder.”

Science Daily: Long-Time Cannabis Use Associated With Psychosis

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Scientists Have Discovered Booze That Won’t Give You A Hangover

Soju

Booze, for all its magical wonder, still has big drawbacks: You can’t sober up quickly, and you often get a hangover. Now Korean researchers have found a way of tweaking booze to limit the fallout — without cutting its strength.

Doctors Kwang-il Kwon and Hye Gwang Jeong of Chungnam National University studied the properties of oxygenated alcohol – booze with oxygen bubbles added – which is a popular concoction in their country. In these drinks, oxygen is added the way carbonation is usually added to soda, and the scientists wanted to know if these oxygenated beverages affected people differently than non-oxygenated ones. The answer was a resounding yes.

i09: Scientists Have Discovered Booze That Won’t Give You A Hangover

(Thanks Blustr)

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<a href="http://psychetect.bandcamp.com/album/return-to-the-wasteland">Awakening by Psychetect</a>

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