Tag Archives: Biopunk

Douglass Rushkoff in Conversation with Genesis P. Orridge (2003 and 2007)

The Believer has finally published Douglas Rushkoff’s interview with Genesis P. Orridge, conducted in 2007 just after Genesis’ wife Lady Jaye passed away:

DR: But, then, Jackie’s passing. Do you experience that on two levels, then? On the level of half of the pandrogene?

GO: Yeah. But I also experience it as a person who is fifty-seven and has been indoctrinated for most of my life to accept a binary world. And feeling a great sense of loss just in a romantic way, as an emotional person. Conceptually, I see that she has just broken through the final perceptual barrier. The human species won’t exist if it carries on replicating pointlessly. I think it’s very clear what we were concerned about when we began this, which was the ever-increasing polarization and reduction of ideas into dogma and paranoia, and this posturing that there’s a right way and a wrong way: I’m right, you’re wrong, and therefore I must attack you. And the whole idea of Pandrogeny is to make that irrelevant, and to bypass that. If we were all pandrogynous, physically and/or mentally, it would be impossible to be at war, because there wouldn’t be a sense of difference all the time.

DR: So does the project continue? You as a lone pandrogene?

GO: It’s not convenient. Because there are lots of things we had in mind that would use both of us in the projects. So I have to try and figure out ways to represent those ideas anyway.

DR: Or start on the new ones. I mean, gender may be an artificial duality perpetrated by DNA and all… but what about death? That’s got to be the biggest, baddest duality of them all. It’s not so very hard to see through gender as a social construction. An illusory divide, like you’ve shown. But death is entirely more convincing. We die, and the people to whom we’ve passed our genes take our place. Death feels like DNA’s last laugh, its final tyranny over us.

The Believer: Douglass Rushkoff in Conversation with Genesis P. Orridge.

Arthur Magazine published another conversation between the two back in 2003. Once upon a time, Rushkoff, Genesis and Grant Morrison were planning to write a book together. It was meant to essentially be a collection of conversations between the three of them. The Arthur interview may give us a sense of what that book may have been like (and the plan for a book may help explain the preoccupation with co-authorship in the interview). It’s also interesting to Rushkoff talk about themes that later became the basis of his books Life Inc and Program or Be Programmed:

DR: That’s why for me the open-source software movement is such a terrific allegory and practice for accepting the fact that we live in a malleable reality. Or certainly for accepting that a hell of a lot more of our world is programmable software than we’ve previously thought. There might be some hardware down there somewhere, but we haven’t got close to that yet. People are starting to accept that they have indeed been the programmers, whether they were witting or not, and that they’re actively programming the world we live in. I think it’s healthy for people to realize this. I think that then they start to experience everything—from their bodies to the air we breathe—as a medium through which they can create and transmit their story.

G P-O: Absolutely. Well you know that Burroughs and Gysin used to say, In a pre-recorded universe, who made the first recording? I’ve thought about that a lot. And what it led me to wasn’t so much wondering about that question, because I think you’re right, it doesn’t matter, actually, but what it did make me realize is that the entire planet is a recording device. That, as you and I are speaking now, on this planet, there is, certainly it seems that way, and we’ll probably find more, there’s some kind of data recorded—whether it be fossils, geological strata—

DR: [laughing]: Or the digital cassette that we’re recording on right now.

See also: my interview with Rushkoff.

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Direct-To-Consumer Genetic Tests May Wildly Overestimate Your Risk of Disease

Direct-to-consumer (DTC) genetic tests give inaccurate predictions of disease risks and many European geneticists believe that some of them should be banned, the annual conference of the European Society of Human Genetics heard May 31.

Although the predictive ability of the DTC tests in the study was moderate for all diseases, both companies assigned an increased risk to a substantial part of the group. Yet the risk of disease in this group was often not substantially higher than the risk in the rest of the population studied. For AMD, the disease with the highest predictive ability, both companies assumed that the risk in the population was around 8%. Of all subjects designated as having an increased risk, 16% using the 23andMe risk estimations and 19% using deCODEme’s estimations would develop AMD, compared to the 4% found in the rest of the population studied. [...]

“deCODEme predicted risks higher than 100% for five out of the eight diseases,” Ms Kalf will say. “This in itself should be enough to raise considerable concern about the accuracy of these predictions — a risk can never be higher than 100%. In the case of AMD one in every 200 individuals in the group would have received a predicted risk of higher than 100%, suggesting that they would definitely develop the disease.”

Science Daily: Direct-To-Consumer Genetic Tests Neither Accurate in Their Predictions nor Beneficial to Individuals, Study Suggests

(via Edward Borasky)

Oh well, at least we’ll always have palm reading.

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Scientists Can Now Rewrite DNA

TAG

MIT and Harvard researchers have developed technologies that could be used to rewrite the genetic code of a living cell, allowing them to make large-scale edits to the cell’s genome. Such technology could enable scientists to design cells that build proteins not found in nature, or engineer bacteria that are resistant to any type of viral infection.

The technology, described in the July 15 issue of Science, can overwrite specific DNA sequences throughout the genome, similar to the find-and-replace function in word-processing programs. Using this approach, the researchers can make hundreds of targeted edits to the genome of E. coli, apparently without disrupting the cells’ function.

MIT News: Scientists unveil tools for rewriting the code of life

(via Richard Yonck)

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Scientists Want to Make a Lysergic Acid Factory from Microbes

Lysergic acid

The headline for The Guardian article about this says the scientists want to make LSD (lysergic acid diethylamide), but the article itself says they want to make lysergic acid (with no diethylamide), a precursor to LSD with other uses.

They said developing biofuels was a terrible business strategy, because fuel was so cheap. Why not make expensive compounds, like pharmaceuticals, instead?

The advice got Wintermute thinking. What was the most valuable compound they could make with the toolkit of synthetic biology? Some research came up with a few candidates including a few very sophisticated cancer drugs. But another compound was up there in monetary terms: LSD. The value by weight was astronomical.

Wintermute and his colleagues had a good laugh about that. But the more they looked into it, the more interesting – and viable – the drug looked. Around 20 tonnes of lysergic acid, a precursor of LSD, are made each year and turned into real medicines, such as nicergoline, a treatment for dementia. The drug is purified from big vats of fungus (which make the compound naturally) using technology developed decades ago.

The Guardian: Harvard scientists to make LSD factory from microbes

(via DrBenway23)

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Bioart Project Seeks to Extract, Copy and Spread William S. Burroughs’s DNA – From a Preserved Turd

William S. Burroughs turd

Here’s a bizarre bioart project. It actually sounds like something out of one of his novels:

1: Take a glob of William S. Burroughs’ preserved shit
2: Isolate the DNA with a kit
3: Make, many, many copies of the DNA we extract
4: Soak the DNA in gold dust
5: Load the DNA dust into a genegun (a modified air pistol)
6: Fire the DNA dust into a mix of fresh sperm, blood and shit
7: Call the genetically modified mix of blood, shit, and sperm a living bioart, a new media paint, a living cut-up literary device and/or a mutant sculpture.

HP+: Mutate or Die: a W.S. Burroughs Biotechnological Bestiary

(via Boing Boing)

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Can You Imagine a Future Where London Police Bees Conduct Genetic Surveillance?

genetic surveillance warning

Designer Thomas Thwaites (who built this DIY toaster with iron ore gathered by hand) has created a project called “Policing Genes,” envisioning a future in which bees are used for genetic surveillance:

Other than a few obvious illegal narcotic plants, it hadn’t occurred to me that the genetics of what is growing in a person’s garden could become a police matter. Even more intriguing/trippy was the possibility of the police using bees for surveillance and for forensically identifying the pollen that the bees came back with. If that pollen is genetically outside of the law, the police could use the bees to track a person right to the house he or she lives in. [...]

Thomas Thwaites, however, has put a great deal of thought into genetic engineering and the policing of those genes. Thwaites pointed out that the ability to insert genes into plants is now DIY technology available to both the amateur and the criminal. “Policing Genes speculates that, like other technologies, genetic engineering will also find a use outside the law, with innocent-looking garden plants being modified to produce narcotics and unlicensed pharmaceuticals.”

Computerworld: Police bees for surveillance, tracking and buzzzsting biohackers?

Policing Genes

See also:

We Make Money Not Art’s interview with Thwaites

Biopunk: the biotechnology black market

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Hong Kong Group Building Encrypted Bacterial Data Storage

Chinese University of Hong Kong iGem

Data encryption and storage has always been an important branch of research in computer engineering. In our project, we explored the possibility of harnessing a biological system as an alternative solution for data en/decryption and storage. Using bacteria as the information storage device is not new. However the practicability of previous research is being doubt due to the limited size of information available to be inserted into the bacteria.

We recognized the current barricades in developing a truly useful system and we forecasted the indispensable modules that one would be anticipating when putting fantasy into reality. This year, we have proposed a model that is a true, massively parallel bacterial data storage system.

In addition we have created an encryption module with the R64 Shufflon-Specific Recombinase to further secure the information. Together with the data proof-read/correction and random access modules developed, our expectation is high – we believe this could be an industrial standard in handling large scale data storage in living cells.

Team:Hong Kong-CUHK – 2010.igem.org

(via Wade)

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Vat Grown Biker Jacket

Biocouture

Unlike the tiny, mouse-sized leather jacket vat grown from mouse and human cells I posted about a few years ago, this jacket is grown from bacteria and green tea and can apparently fit a human.

Ecouterre: U.K. Designer “Grows” an Entire Wardrobe From Bacteria

Biocouture

(via Boing Boing)

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The Rise Of ‘Transplant Tourism’ – Should Organ Sales be Legalized?

polycystic kidney

How much is your kidney worth?

In Turkey the prized organ fetches around €2,300, an Indian or Iraqi kidney enriches its former owner by a mere €800, and the World Health Organisation (WHO) estimates the going price on the black market to be about €4,000.

But when you consider that wealthy clients will later pay well over €100,000 for the kidney, this massive profit margin would appear to guarantee a lucrative future for the international trade in human organs if it continues unchecked.

Irish Health: The Rise Of ‘Transplant Tourism’

Should organ sales be legalized and regulated instead of relying on voluntary donations?

Photo by euthman / CC

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Ultra cheap nanochips could be built from DNA

DNA waffle

In his latest set of experiments, Chris Dwyer, assistant professor of electrical and computer engineering at Duke’s Pratt School of Engineering, demonstrated that by simply mixing customized snippets of DNA and other molecules, he could create literally billions of identical, tiny, waffle-looking structures.

Dwyer has shown that these nanostructures will efficiently self-assemble, and when different light-sensitive molecules are added to the mixture, the waffles exhibit unique and “programmable” properties that can be readily tapped. Using light to excite these molecules, known as chromophores, he can create simple logic gates, or switches.

PhysOrg: DNA could be backbone of next generation logic chips

(via Theoretick)

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